Liverpool’s injury woes worsened as was forced to leave the field during at Anfield.
The Reds’ captain, already filling in at centre-back because of injuries to and will undergo assessment today.
Jurgen Klopp was forced to bring on the relatively inexperienced but, despite the 23-year-old stepping in well, Liverpool went on to lose the game 2-0 – their fourth consecutive loss at Anfield.
“It’s the groin/adductor region and nobody in the medical department was positive about it,” said manager after the game.
“It doesn’t look good, but we have to wait, of course, for the scan tomorrow, hopefully.”
It is possible that such an injury could keep Henderson out for at least six weeks.
It was initially expected that he would be out for six to ten weeks but it seems clear now that he is touch and go to make it back before the end of the season.
Divock Origi and Caoimhin Kelleher were once again absent from the bench for the 3-1 defeat to Real Madrid on Tuesday night, and no timescale has been given on when they will return to action.
Neither player has been pictured back in training with Origi having missed the last three games, while Kelleher has not been seen since being named as a substitute for the first leg of the Champions League last 16 tie against RB Leipzig.
Virgil van Dijk (knee), Joel Matip (ankle) and Joe Gomez (knee) will not play again this campaign, with all expected to return when pre-season begins.