Manchester United forward Marcus Rashford is already back in the gym after recovering from shoulder surgery.
The 23-year-old was due to be available for selection again at the start of November and, while manager Ole Gunnar Solskjaer says the player is still quite a way from making his comeback, there is now optimism that an early return is possible.
Amad Diallo will be out for six weeks with a muscular problem he picked up in training last week. The 19-year-old was all set to make the loan switch to Feyenoord but he will now stay at Carrington to aid his recovery.
Scott McTominay is expected to be out of action for around a month after undergoing surgery on a troublesome groin issue, while Alex Telles remains sidelined with an ankle problem.
Dean Henderson should be back in contention after the international break, having now recovered from the virus, while Phil Jones is still building up his fitness after a year out with a knee injury.
